Two sample MR report
TUFM_Conventional Dendritic Cell against UKB-b-18436
Date: 13 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 15 | 0.1079742 | 0.0853906 | 0.2282599 |
| Weighted median | 15 | 0.0374110 | 0.0079771 | 0.0000027 |
| Inverse variance weighted | 15 | 0.0315406 | 0.0060454 | 0.0000002 |
| Simple mode | 15 | 0.0383872 | 0.0121165 | 0.0068400 |
| Weighted mode | 15 | 0.0381307 | 0.0119944 | 0.0066937 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 11.23474 | 13 | 0.5911597 |
| Inverse variance weighted | 12.03999 | 14 | 0.6030909 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| -0.0399241 | 0.0444908 | 0.3858457 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0.000325 | 0 | TRUE | 0.0880532 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
